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DemeTECH’s Polyglycolic Acid (PGA) suture is a coated, braided synthetic absorbable suture, composed of the homopolymer of glycolic acid and coated with polycaprolactone and calcium stearate. The PGA Suture is available in violet and colorless from sizes: USP 8/0 to USP 2.
Intended Use
PGA Suture is indicated for use in general soft tissue approximation and / or ligation, including use in ophthalmic surgery.
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A slight tissue inflammation may occur when PGA Sutures are placed in tissue, which is characteristic of foreign body response, which is followed by gradual encapsulation by connective tissue.
After which absorption by hydrolysis begins, where the polymer degrades to glycolic acid, which is absorbed by the body. PGA elicits a minimal acute inflammatory reaction in tissues, which is followed by gradual encapsulation of the suture by fibrous connective tissue.
Progressive loss of tensile strength and eventual absorption of PGA synthetic absorbable sutures occurs by means of hydrolysis, where the polymer degrades to either glycolic acid or glycolic and lactic acids which are subsequently absorbed and metabolized by the body. Absorption begins as a loss of tensile strength without appreciable loss of mass.
Implantation studies indicate that PGA retains approximately 84 % of its original tensile strength at two weeks post implantation, with approximately 51% remaining at three weeks. Absorption of PGA absorbable synthetic suture is essentially complete between 60 and 90 days.
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DemeTECH’s Polyglycolic Acid (PGA) suture is a coated, braided synthetic absorbable suture, composed of the homopolymer of glycolic acid and coated with polycaprolactone and calcium stearate. The PGA Suture is available in violet and colorless from sizes: USP 8/0 to USP 2.
Intended Use
PGA Suture is indicated for use in general soft tissue approximation and / or ligation, including use in ophthalmic surgery.
Actions
A slight tissue inflammation may occur when PGA Sutures are placed in tissue, which is characteristic of foreign body response, which is followed by gradual encapsulation by connective tissue.
After which absorption by hydrolysis begins, where the polymer degrades to glycolic acid, which is absorbed by the body. PGA elicits a minimal acute inflammatory reaction in tissues, which is followed by gradual encapsulation of the suture by fibrous connective tissue.
Progressive loss of tensile strength and eventual absorption of PGA synthetic absorbable sutures occurs by means of hydrolysis, where the polymer degrades to either glycolic acid or glycolic and lactic acids which are subsequently absorbed and metabolized by the body. Absorption begins as a loss of tensile strength without appreciable loss of mass.
Implantation studies indicate that PGA retains approximately 84 % of its original tensile strength at two weeks post implantation, with approximately 51% remaining at three weeks. Absorption of PGA absorbable synthetic suture is essentially complete between 60 and 90 days.
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